Search results for "african american"
showing 10 items of 29 documents
Associations between cardiovascular disease, cancer, and very low high-density lipoprotein cholesterol in the REasons for Geographical and Racial Dif…
2018
AbstractAimsRelatively little is known about the health outcomes associated with very low plasma concentrations of high-density lipoprotein cholesterol (HDL-C) mainly because of the small numbers of individuals with such extreme values included in clinical trials. We, therefore, investigated the association between low and very low HDL-C concentration at baseline and incident all-cause-mortality, death from malignant disease (i.e. cancer), and with fatal or non-fatal incident coronary heart disease (CHD) in individuals from the Reasons for Geographical And Racial Differences in Stroke (REGARDS) study.Methods and resultsAnalysis was based on 21 751 participants from the REGARDS study who wer…
Genome-Wide Association Studies of the PR Interval in African Americans.
2011
The PR interval on the electrocardiogram reflects atrial and atrioventricular nodal conduction time. The PR interval is heritable, provides important information about arrhythmia risk, and has been suggested to differ among human races. Genome-wide association (GWA) studies have identified common genetic determinants of the PR interval in individuals of European and Asian ancestry, but there is a general paucity of GWA studies in individuals of African ancestry. We performed GWA studies in African American individuals from four cohorts (n = 6,247) to identify genetic variants associated with PR interval duration. Genotyping was performed using the Affymetrix 6.0 microarray. Imputation was p…
Genome-wide and gene-centric analyses of circulating myeloperoxidase levels in the charge and care consortia
2013
Increased systemic levels of myeloperoxidase (MPO) are associated with the risk of coronary artery disease (CAD). To identify the genetic factors that are associated with circulating MPO levels, we carried out a genome-wide association study (GWAS) and a gene-centric analysis in subjects of European ancestry and African Americans (AAs). A locus on chromosome 1q31.1 containing the complement factor H (CFH) gene was strongly associated with serum MPO levels in 9305 subjects of European ancestry (lead SNP rs800292; P = 4.89 × 10(-41)) and in 1690 AA subjects (rs505102; P = 1.05 × 10(-8)). Gene-centric analyses in 8335 subjects of European ancestry additionally identified two rare M…
Associations between leprosy and serum protein groups
1970
Serum protein group typings were done on a sample of n=173 adult healthy Negroes from the Macua tribe in Mozambique and on n=129 leprous individuals from the same tribe. Unfortunately, the type of leprosy is not known. Whilst between leprosy and haptoglobins, transferrins and Pi proteins no associations could be observed, statistically significant associations between leprosy and ceruloplasmin resp. β2 I were found. It is pointed out that these associations should be confirmed by further research on other populations and with respect to type and process of leprosy, until biological and population genetical interpretations will be possible.
Disclosure to God as a Mediator Between Private Prayer and Psychological Well-Being in a Christian Sample.
2021
AbstractAlthough a number of studies have reported the psychological and physical benefits of prayer, only a few have examined the means by which prayer affects health. Winkeljohn Black et al. (J Relig Health 54(2):540–553, 2015. 10.1007/s10943-014-9840-4) found disclosure to God as a mediator in the relationship between prayer and mental health. In their study, the authors used Poloma and Pendleton’s (Rev Relig Res 31(1):46–53, 1989. https://doi.org/10.2307/3511023, ) model of prayer. This study examined whether disclosure to God as a mediator can be upheld with Laird et al.’s (Int J Psychol Relig 14(4):251–272, 2004) prayer model. The study included 285 Polish adults (50.2% of women), age…
The development of African American Vernacular English in two fiction texts: a case study
2009
Afroamerikkalainen englanti on Pohjois-Amerikassa ristiriitaisessa asemassa. Kielitieteilijät eivät ole yhteisymmärryksessä kielen syntyperästä ja näin koko kieli ja sen oikeellisuus on kyseenalaistettu Amerikassa. Kielen käyttäjät ovat useimmiten mustia amerikkalaisia, joista useat ovat joutuneet pilkan kohteiksi puhetyylinsä vuoksi. Nykyään monet mustat jopa pitävät kieltään vain slangina tai muuten virheellisenä. Siksi lisää tutkimuksia afroamerikkalaisesta englannista tarvittaisiin. Tässä tutkimuksessa vertailtiin kahta fiktiivistä afroamerikkalaista tekstiä toisiinsa, jotta nähtiin millaisia eroja ja yhtäläisyyksiä kirjailijoiden kielenkäytössä oli. Näistä eroista tehtiin myös johtopä…
Rasisms un noziegumi Voltera Moslija detektīvromānos "Velns zilā kleitā", "Sarkanā nāve" un "Balts tauriņš"
2019
Bakalauradarbs „Rasisms un kriminālsVolteraMoslijadetektīvromānos „Velnszilākleitā”, „Sarkanānāve” un „Baltstauriņš”” analizēnosauktus romānus ar uzsvaru uz aprakstītas kriminālas situācijas un rasismu ASV kopumā un Kalifornijā. Ņemot vērā ka romāni pieder pie daiļliteratūras un autora situācijas redzējums var atšķirties no reālas situācijas ASV četrdesmitajos un piecdesmitajos gados, ir savākta un apkopota informācija par rasisma un segregācijas vēsturi ASV, lai izprastu, cik patiess priekšstats par situāciju autors dod. Bakalaura darba mērķis ir atrast rasisma un segregācijas piemērus romānos; saprast, kā atrastie piemēri ilustrē rasisma, augstu ieslodzīto un apsūdzēto afroamerikāņu īpats…
Genome-wide association studies identify 137 loci for DNA methylation biomarkers of ageing
2020
AbstractBiological ageing estimators derived from DNA methylation (DNAm) data are heritable and correlate with morbidity and mortality. Leveraging DNAm and SNP data from >41,000 individuals, we identify 137 genome-wide significant loci (113 novel) from meta-analyses of four epigenetic clocks and epigenetic surrogate markers for granulocyte proportions and plasminogen activator inhibitor 1 levels, respectively. We report strong genetic correlations with longevity and lifestyle factors such as smoking, education, and obesity. Significant associations are observed in polygenic risk score analysis and to a lesser extent in Mendelian randomization analyses. This study illuminates the genetic …
Redemption and home in the african american city upon a hill: hannah crafts’s the bondwoman’s narrative.
2019
The Bondwoman’s Narrative (1857) is a novel in which the black female slave Hannah Crafts aims at the remodeling of her society and to gain self–assertion through a deeply Christian commitment and a total and honest respect to the values it impinges drawing broadly on the Bible and reshaping biblical imagery to convey her message and to submit her subjectivity and her Americanness. By using the national continuum of jeremiad rhetoric and her attachment to the values of the Christian creed, the novel partakes and yet takes a different direction from slave narratives by cagily forerunning Du Bois’s praised theory of the double consciousness. In so doing, it positions its protagonist as the fi…
The Affective Turn and Sacred Femininity in African American Women's Literature
2017
Després del llarg viatge a través de l’Atlàntic a bord dels vaixells esclavistes, els africans van veure’s obligats a enfrontar-se a la seua completa alienació física, social i també espiritual en les terres de l’anomenat ‘Nou Món’. La seua anterior concepció de l’univers com a un lloc on poden exisitir-hi un ventall il·limitat de déus es va veure estroncat per la imposició social d’un univers on l’esclau va perdre tant el seu sentit d’espai com de temps. Així doncs, la evolució històrica del poble afroamericà s’esmerça en conrear una concepció sagrada del seu entorn des del mateix moment en que arriben a terres americanes. Aquesta obligada gestació espiritual els commina a acollir i, alhor…